New prostate cancer biomarkers validated by independent studies

        Isabelle Guyon, Thomas A. Stamey, Herbert A. Fritsche, and Stephen D. Barnhill
Technical report. Results presented as a poster at the Molecular Medicine Tri-Conference 2005 in San Francisco.

With our analytical tools we have analyzed microarray data with over 20,000 genes. We have discovered molecular patterns characteristic of zonal and histological tissue classification of the prostate. We have found promising prostate cancer biomarkers yielding 90% sensitivity and specificity on completely independently collected data. We have also found promising diagnostic markers and new drug targets for BPH.

Keywords: Biomarkers / DNA microarrays /  Prostate Cancer / SVM

[ next paper ]