Isabelle Guyon, Hans-Marcus Bitter, Zulfikar Ahmed, Michael Brown, and Jonathan Heller.
In proceedings BISC FLINT-CIBI 2003 workshop, Berkeley, Dec. 2003.
We address problems of classification in which the number of input components (variables, features) is very large compared to the number of training samples. In this setting, it is often desirable to perform a feature selection to reduce the number of inputs, either for efficiency, performance, or to gain understanding of the data and the classifiers. We compare a number of methods on mass-spectrometric data of human protein sera from asymptomatic patients and prostate cancer patients. We show empirical evidence that, in spite of the high danger of overfitting, non-linear methods can outperform linear methods, both in performance and number of features selected.
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